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Albumin, Fatty Acid Free

Cat. No. M10361
Albumin, Fatty Acid Free Structure
Synonym:

Bovine Serum Albumin; BSA Fatty free

Size Price Availability Quantity
5g USD 72  USD72 In stock
10g USD 120  USD120 In stock
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Quality Control & Documentation
  • Purity: >98%, for molecular biology
  • COA
  • MSDS
Biological Activity

This product is bovine serum albumin (Fatty Acid Free BSA) without Fatty Acid, its Fatty Acid content is very low (0.02%), easy to dissolve.

Chemical Information
CAS Number 9048-46-8
Solubility (25°C) Water 50 mg/mL
Storage 2-8°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Alexander H Penn, et al. Shock. Fatty Acid-Saturated Albumin Reduces High Mortality and Fluid Requirements in a Rat Model of Hemorrhagic Shock Plus Tourniquet and Hypotensive Resuscitation

[2] James P C Coverdale, et al. Biochim Biophys Acta Mol Cell Biol Lipids. Crosstalk between zinc and free fatty acids in plasma

[3] P A Schwartz, et al. Pharmacology. Effect of free fatty acid concentration on furosemide binding to human serum albumin

[4] B Hennig, et al. Arteriosclerosis. Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers

[5] P H Figard, et al. J Lipid Res. Free fatty acid release from endothelial cells

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Keywords: Albumin, Fatty Acid Free, Bovine Serum Albumin; BSA Fatty free supplier, Western Blot, inhibitors, activators


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