Free shipping on all orders over $ 500

Avidin (from egg white)

Cat. No. M22515
Avidin (from egg white) Structure
Synonym:

Immunopure Avidin

Size Price Availability Quantity
5mg USD 220  USD220 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: ≥98%, 10-15 units/mg protein (E1%/280)
  • COA
  • MSDS
Biological Activity

Avidin is homotetrameric protein (68kDa) that is obtained from egg whites. Avidin forms an extremely strong complex with d-biotin (Kd ~ 10-15). This activity has made both avidin and biotin extremely useful labels in immunochemical methods of detection and quantitation. The use of avidin-biotin immunoassay enhances the sensitivity of the technique and facilitates the detection of antigens in low quantities.

Chemical Information
CAS Number 1405-69-2
Solubility (25°C)
Storage -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Vesa P Hytnen. Methods Enzymol. (Strept)avidin as a template for ligands other than biotin: An overview

[2] Akshay Jain, et al. J Control Release. The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis

[3] Hanna P Lesch, et al. Expert Opin Drug Deliv. Avidin-biotin technology in targeted therapy

[4] F M Richards. Methods Enzymol. Avidin-biotin technology. Reflections

[5] N M Green. Adv Protein Chem. Avidin

Related Products
Dextran (Mw 150000)

Dextran is a multipurpose branched glucan, which can improve plasma colloid osmotic pressure, increase blood volume, reduce platelet adhesion, inhibit red blood cell aggregation, reduce blood viscosity, reduce peripheral circulation resistance, and unclog microcirculation.

Zeatin

Zeatin is a coconut milk-derived plant hormone and is a common plant cytokinin that is found in the developing or meristematic tissues and organs such as roots, shoot apex, immature organs, and others.

Carbidopa monohydrate

Carbidopa monohydrate is a dopa decarboxylase (DDC) inhibitor, which can be used for the research of Parkinson's disease. Carbidopa monohydrate is also a selective aryl hydrocarbon receptor (AhR) modulator.

Poly-L-lysine (MW 15000~30000)

Poly-L-lysine (MW 15000~30000)

Poly-L-lysine (MW 30000~70000)

Poly-L-lysine (MW 30000~70000)

  Catalog
Abmole Inhibitor Catalog




Keywords: Avidin (from egg white), Immunopure Avidin supplier, inhibitors, activators

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.