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AK-1 is a cell permeable, potent and specific SIRT2 inhibitor with an IC50 of 12.5 μM, it induced proteasomal degradation of the Snail transcription factor.
| Molecular Weight | 403.45 |
| Formula | C19H21N3O5S |
| CAS Number | 330461-64-8 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] F Gloria-Bottini, et al. Ak(1) genetic polymorphism and season of conception
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