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AEM1 

Cat. No. M27668

All AbMole products are for research use only, cannot be used for human consumption.

AEM1  Structure

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Quality Control & Documentation
Biological Activity

AEM1 is a Nrf2 inhibitor. AEM1 reduces the expressions of Nrf2-dependent genes in A549 cells and inhibits the growth of A549 cells in vitro and in vivo.

Chemical Information
Molecular Weight 379.41
Formula C20H14FN3O2S
CAS Number 1030123-90-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anne E Magurran. Curr Biol. Measuring biological diversity

[2] Anne E Magurran. BMC Biol. The important challenge of quantifying tropical diversity

[3] Michael J Bollong, et al. ACS Chem Biol. A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer

[4] Gesine Hoffmann, et al. J Biol Chem. A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer

[5] Bakul Rani Debi, et al. J Plant Physiol. Defects in root development and gravity response in the aem1 mutant of rice are associated with reduced auxin efflux

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  Catalog
Abmole Inhibitor Catalog




Keywords: AEM1  supplier, Keap1-Nrf2, inhibitors, activators

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