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Adenine hemisulfate

Cat. No. M13639
Adenine hemisulfate Structure
Synonym:

6-Aminopurine hemisulfate; Vitamin B4 hemisulfate

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1g USD 25  USD25 In stock
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Quality Control & Documentation
Biological Activity

Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

Chemical Information
Molecular Weight 233.21
CAS Number 321-30-2
Solubility (25°C) DMSO 90 mg/mL
Water 5 mg/mL (ultrasonic and heat to 50°C)
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Gulsun Memi, et al. Chin J Physiol. Adropin and spexin hormones regulate the systemic inflammation in adenine-induced chronic kidney failure in rat

[2] Burak Yazgan, et al. Exp Biol Med (Maywood). Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin

[3] Catalina Restrepo-Osorio, et al. BMC Res Notes. Efficient direct shoot organogenesis and genetic stability in micropropagated sacha inchi (Plukenetia volubilis L.)

[4] Micah E Stevens, et al. Plant Cell Rep. Agrobacterium-mediated genetic transformation and plant regeneration of the hardwood tree species Fraxinus profunda

[5] Liping Tong, et al. Mutat Res. Low concentration of exogenous carbon monoxide protects mammalian cells against proliferation induced by radiation-induced bystander effect

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Keywords: Adenine hemisulfate, 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate supplier, DNA/RNA Synthesis, inhibitors, activators


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