Abbv-cls-484 is a potent inhibitor of PTPN1 or PTPN2 with subnanomolar activity.
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Related Phosphatase Products|
Tautomycetin is a potent and specifical PP1 inhibitor with the potential apoptosis-inducing activity. Tautomycetin inhibits purified PP1 and PP2A enzymes with IC50s of 1.6 nM and 62 nM, respectively.
|L-Ascorbic Acid 2-phosphate (magnesium salt hydrate)
L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) is a long-term vitamin C derivative that can stimulate the expression and formation of collagen. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) can be used as a medium to supplement osteogenic differentiation of human adipose stem cells (hASCs). Increased alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation.
MSI-1436 is a non-competitive inhibitor of PTP1B with a selective IC50 of 1 μM and an IC50 value of 224 μM for TCPTP.
|Etidronic acid disodium
Etidronate disodium (Etidronate disodium; HEDPA disodium; HEDP disodium) is a nonamino bisphosphonate with protein tyrosine phosphatase (PTP) inhibitory activity.
L-Homoarginine is a specific inhibitor of liver-type alkaline phosphatase.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.