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Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1. Abatacept binds to antigen presenting cells CD80 and CD86, blocks costimulatory signals and inhibits T cell activation, and is used in the study of rheumatoid arthritis and juvenile rheumatoid arthritis.
| CAS Number | 332348-12-6 |
| Form | Solid |
| Storage | 4°C, protect from light, do not freeze. |
[5] Hannah A Blair, et al. Drugs. Abatacept: A Review in Rheumatoid Arthritis
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Products are for research use only. Not for human use. We do not sell to patients.
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