Certificate of Analysis

 

Product Name: Abatacept
Catalog Number: M11481
CAS Number: 332348-12-6

Physical and Chemical Properties
Form: Solid
Storage: 4°C, protect from light, do not freeze.
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1. Abatacept binds to antigen presenting cells CD80 and CD86, blocks costimulatory signals and inhibits T cell activation, and is used in the study of rheumatoid arthritis and juvenile rheumatoid arthritis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.