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A2764 dihydrochloride is a selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1) with IC50 of 11.8 μM for the activated mTRESK channel. A2764 dihydrochloride has the potential for probing the role of TRESK channel in migraine and nociception.
| Molecular Weight | 351.7 |
| Formula | C15H21Cl3N2O |
| CAS Number | 861038-72-4 |
| Solubility (25°C) | DMSO 70 mg/mL Water 70 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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