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6-TAMRA-SE

Cat. No. M13764
6-TAMRA-SE Structure
Synonym:

6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester

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Quality Control & Documentation
Biological Activity

6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing.

Chemical Information
Molecular Weight 527.52
CAS Number 150810-69-8
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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Keywords: 6-TAMRA-SE, 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester supplier, Fluorescent Dye, inhibitors, activators


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