Free shipping on all orders over $ 500

5-Methylcytosine

Cat. No. M13637

All AbMole products are for research use only, cannot be used for human consumption.

5-Methylcytosine Structure
Size Price Availability Quantity
500mg USD 25  USD25 In stock
1g USD 40  USD40 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development.

Chemical Information
Molecular Weight 125.13
CAS Number 554-01-8
Solubility (25°C) DMSO 8.33 mg/mL
Water 7.14 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yaqi Gao, et al. RNA Biol. RNA 5-methylcytosine modification and its emerging role as an epitranscriptomic mark

[2] Yibin Liu, et al. Nat Biotechnol. Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

[3] Katherine E Bohnsack, et al. Genes (Basel). Eukaryotic 5-methylcytosine (m⁵C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease

[4] Lukas Trixl, et al. Wiley Interdiscip Rev RNA. The dynamic RNA modification 5-methylcytosine and its emerging role as an epitranscriptomic mark

[5] Bi-Feng Yuan. Adv Clin Chem. 5-methylcytosine and its derivatives

Related DNA/RNA Synthesis Products
Dencatistat

Dencatistat (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC50 value of ≤ 0.1 μM.

Antipain dihydrochloride

Antipain dihydrochloride is a protease inhibitor. Antipain dihydrochloride inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride also restricts uterine DNA synthesis and function in mice.

Tetrahydrouridine

Tetrahydrouridine (THU) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.

Crisnatol

Crisnatol (BWA770U) is a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells. Crisnatol (BWA770U) is also an orally active and anticancer agent.

Caf1-IN-1

Caf1-IN-1 is inhibitor for ribonuclease Caf1 with an IC50 of 0.59 µM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 µM.

  Catalog
Abmole Inhibitor Catalog




Keywords: 5-Methylcytosine supplier, DNA/RNA Synthesis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.