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4',5,7-Trimethoxyflavone

Cat. No. M18266

All AbMole products are for research use only, cannot be used for human consumption.

4',5,7-Trimethoxyflavone Structure
Size Price Availability Quantity
5mg USD 50  USD50 In stock
10mg USD 75  USD75 In stock
20mg USD 125  USD125 In stock
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Quality Control & Documentation
Biological Activity

5,7,4'-Trimethoxyflavone is a natural product isolated from the Thai plant Kaempferia parviflora (KP) and a CFTR activator with an EC50 of 64 μM. In addition, 5,7,4'-Trimethoxyflavone induces apoptosis, increases the activation of caspase-3 protein hydrolysis, and the degradation of poly (ADP-ribose) polymerase (PARP) protein. 

Chemical Information
Molecular Weight 312.32
Formula C18H16O5
CAS Number 5631-70-9
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qin-Ge Ma, et al. Zhongguo Zhong Yao Za Zhi. [Studies on flavonoids from Cirsium setosum]

[2] Qi-Shi-San Wu, et al. Zhong Yao Cai. [Study on chemical constituents of Ixeris chinensis]

[3] Yi Liu, et al. Biochem Pharmacol. Effects of the natural flavone trimethylapigenin on cardiac potassium currents

[4] Pattara Sawasdee, et al. Phytother Res. Anticholinesterase activity of 7-methoxyflavones isolated from Kaempferia parviflora

[5] Horst Fischer, et al. Cell Physiol Biochem. Activation of the CFTR Cl- channel by trimethoxyflavone in vitro and in vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: 4',5,7-Trimethoxyflavone supplier, CFTR, inhibitors, activators

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