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3-Chlorodiphenylamine

Cat. No. M27631

All AbMole products are for research use only, cannot be used for human consumption.

3-Chlorodiphenylamine Structure
Synonym:

3-

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Quality Control & Documentation
Biological Activity

3-Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (Kd=6 µM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+-sensitizing compounds due to its small size, and can be used for systolic heart failure research.

Chemical Information
Molecular Weight 203.67
Formula C12H10ClN
CAS Number 101-17-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Svetlana B Tikunova, et al. J Gen Physiol. 3-Chlorodiphenylamine activates cardiac troponin by a mechanism distinct from bepridil or TFP

[2] K Nakata. J Biosci Bioeng. Two glycolipids increase in the bioremediation of halogenated aromatic compounds

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Keywords: 3-Chlorodiphenylamine, 3- supplier, Potassium Channel, inhibitors, activators

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