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17-PA

Cat. No. M6319

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17-PA Structure
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10mg USD 980  USD980 Custom Synthesis
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Quality Control & Documentation
Biological Activity

17-PA is a selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors. Selectively reduces the effects of 5α-reduced steroids compared to 5β-reduced steroids and displays no effect on potentiation evoked by barbiturates and benzodiazepines. Attenuates 3α,5α-THP-induced loss of righting reflex and total sleep time following i.c.v administration in rats.

Chemical Information
Molecular Weight 350.54
Formula C25H34O
CAS Number 694438-95-4
Solubility (25°C) DMSO 8.76 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alejandro Ciocci Pardo, et al. Cardioprotective effects of N-methylacetazolamide mediated by inhibition of L-type Ca 2+ channel current

[2] Lambed Tatah, et al. Analysis of Cameroon's Sectoral Policies on Physical Activity for Noncommunicable Disease Prevention

[3] Joao G Ramos, et al. Cardiovascular magnetic resonance 4D flow analysis has a higher diagnostic yield than Doppler echocardiography for detecting increased pulmonary artery pressure

[4] Stephen Ellenbogen, et al. Contrasting mental health correlates of physical and sexual abuse-related shame

[5] Marielle van der Deijl, et al. Participation levels of physical activity programs for community-dwelling older adults: a systematic review

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Keywords: 17-PA supplier, GABA Receptor, inhibitors, activators

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