Free shipping on all orders over $ 500

Recently Added

YAP YAP (Yes-associated protein)

Inhibitor/Activator

Cat.No.	Name	Information
M40561	GNE-7883	GNE-7883 is a potent pan-TEAD small molecule inhibitor that inhibits the interaction between YAP/TAZ and TEAD through altered regulation. It possesses antiproliferative and antitumor activity and can be used in tumor-related studies.
M31263	VT02956	VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1, 0.52 nM for LATS2). VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and tumor organoids.
M31170	MSC-4106	MSC-4106 is an orally active inhibitor of the YAP/TAZ-TEAD complex that blocks the auto-palmitoylation of TEAD1 and TEAD3, and can be used for tumor-related studies.
M29628	VT104	VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer.