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VT104 

Cat. No. M29628

All AbMole products are for research use only, cannot be used for human consumption.

VT104  Structure

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Quality Control & Documentation
Biological Activity

VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer.

Chemical Information
Molecular Weight 420.43
Formula C25H19F3N2O
CAS Number 2417718-25-1
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] L Uccioli, et al. Diabetes. Abnormal agonist-stimulated cardiac parasympathetic acetylcholine release in streptozocin-induced diabetes

[2] Yoshinobu Saito, et al. Gastroenterology. A Therapeutically Targetable TAZ-TEAD2 Pathway Drives the Growth of Hepatocellular Carcinoma via ANLN and KIF23

[3] Ettore Amato, et al. BMC Infect Dis. Identification of a major Listeria monocytogenes outbreak clone linked to soft cheese in Northern Italy - 2009-2011

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  Catalog
Abmole Inhibitor Catalog




Keywords: VT104  supplier, YAP, inhibitors, activators

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