About 9 results found for searched term "YAP" (0.054 seconds)
Cat.No. | Name | Target |
---|---|---|
M4540 | Scutellarein | Src-bcr-Abl |
6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone | ||
Scutellarein is a natural flavonoid with anti-inflammatory effects. | ||
M10224 | YAP-TEAD-IN-1 TFA | YAP |
YAP-TEAD-IN-1 TFA is a competitive inhibitor of YAP-TEAD interaction with IC50 of 25 nM. | ||
M14938 | YAP/TAZ inhibitor-1 | YAP |
YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor with an IC50 of <0.100 μΜ in firefly luciferase assay. | ||
M16650 | 3,6-Dimethoxyapigenin | Flavonoids |
3,6-Dimethoxyapigenin | ||
M18105 | (±)-2-Hydroxy-1-Methoxyaporphine | Metabolite/Endogenous Metabolite |
(±)-2-Hydroxy-1-Methoxyaporphine | ||
M18530 | 8-Hydroxyapigenin | Others |
8-Hydroxyapigenin | ||
M31171 | YAP/TAZ inhibitor-2 | YAP |
YAP/TAZ inhibitor-2 is a potent, orally bioavailable TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM that exhibits anticancer and antiproliferative activity. | ||
M43572 | IAG933 | YAP |
YAP-TEAD-IN-3 | ||
IAG933 is a first-in-class, selective and orally efficacious YAP1/WWTR1(TAZ)-panTEAD protein-protein interaction inhibitor. IAG933 specifically abrogates the interaction between YAP/TAZ coactivators and all four TEAD isoforms, thus selectively inhibiting TEAD-driven transcriptional activity and inducing anti-cancer effects. | ||
M50386 | YAP-TEAD-IN-1 | YAP |
YAP-TEAD-IN-1 is a potent and competitive inhibitor of YAP–TEAD interaction (IC50=25 nM). |
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