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VT02956 

Cat. No. M31263

All AbMole products are for research use only, cannot be used for human consumption.

VT02956  Structure

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Quality Control & Documentation
Biological Activity

VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1, 0.52 nM for LATS2). VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and tumor organoids.

Chemical Information
Molecular Weight 373.45
Formula C22H23N5O
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shenghong Ma, et al. Nat Commun. Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: VT02956  supplier, YAP, inhibitors, activators

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