Inhibitor/Activator
| Cat.No. | Name | Information |
|---|---|---|
| M55697 | β-Tocopherol-d3 | β-Tocopherol-d3 is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol. |
| M31243 | Kojic acid dipalmitate | Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid, a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. |
| M19233 | Kushenol A | Kushenol A (Leachianone E) is a non-competitive tyrosinase inhibitor to block the conversion of L-tyrosine to L-DOPA, shows IC50 and Kivalues of 1.1 μM and 0.4 μM, respectively. |
| M18336 | 2-Methoxycinnamic acid | 2-Methoxycinnamic acid |
| M11498 | 2-Ketoglutaric acid | 2-ketoglutaric acid (alpha-ketoglutaric acid) is an intermediate produced by ATP or GTP in the Krebs cycle. 2-ketoglutaric acid also acts as the main carbon skeleton for nitrogen assimilation. 2-ketoglutaric acid is a reversible inhibitor of Tyrosinase (IC50=15 mM). |
| M11479 | (-)-Taxifolin | (-)-Taxifolin is a low activity isomer of Taxifolin. Taxifolin has important anti-tyrosinase activity. Taxifolin effectively inhibited collagenase with IC50 of 193.3 μM. Taxifolin is an important natural compound with anti-fibrosis effects. Taxifolin is a free radical scavenger with antioxidant capacity. |
| M11129 | Dihydromorin | trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening of hypopigmenting agents. |
| M10991 | Methyl cinnamate | Methyl cinnamate (Methyl 3-phenylpropenoate) is an active ingredient in peppercorns and a versatile natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) has antibacterial activity and is a tyrosinase inhibitor that prevents browning of food. |
| M5281 | XMD16-5 | XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations. |
| M5280 | XMD8-87 | XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations. |
| M4370 | Trifolirhizin | Trifolirhizin is a pterocarpan flavonoid isolated from the root of Sophora flavescoreae. Trifolirhizin showed high tyrosinase inhibitory activity with IC50 of 506 μM. Trifolirhizin has potential anti-inflammatory and anticancer activities. |
| M2618 | Deoxyarbutin | Deoxyarbutin can effectively inhibit tyrosinase activity and melanin synthesis, and obtain significant and lasting whitening effect, with strong antioxidant effect. |
| M56798 | β-Tocopherol | β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. |
| M54424 | Tyrosinase (206-214), human | Tyrosinase (206-214), human (AFLPWHRLF), a 9-amino acid peptide, is a tyrosinase epitope. |
| M53867 | Ac-[Nle4, D-Phe7]-α-MSH (4-10)-NH2 | Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 is a melanotropin, a melanocyte-stimulating hormone. |
| M53834 | Tetrapeptide-30 | Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. |
| M52502 | Diaminopropionoyl tripeptide-33 | Diaminopropionoyl tripeptide-33isa bioactive peptide with protects skin cells from UVA-induced DNA damages and has been reported used as a cosmetic ingredient. |
| M44932 | Methyl rosmarinate | Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase. |
| M44707 | 3-(2,4-Dihydroxyphenyl)propionic acid | 3-(2,4-Dihydroxyphenyl)propanoic acid (DPPacid) is a potent and competitive tyrosinase inhibitor, inhibits L-Tyrosine and DL-DOPA with an IC50 and a Ki of 3.02 μM and 11.5 μM, respectively. |
| M42621 | Tec-IN-1 | Tec-IN-1 is a Tec inhibitor (IC50s of 11.7 μM). |
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