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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9205 | Glasdegib | Glasdegib (PF-04449913) is a potent, orally bioavailable Smoothened (Smo) inhibitor with an IC50 of 4 nM. |
| M8977 | MK-4101 | MK-4101 is a novel SMO antagonist of the Hedgehog Pathway. |
| M2997 | SANT-1 | SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM. |
| M2465 | BMS-833923 | BMS-833923 is an orally bioavailable Smoothened antagonist. |
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