Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M42937 | CVM-05-002 | CVM-05-002 is a PI5P4K inhibitor, with IC50 values of 0.27 μM and 1.7 μM for PI5P4Kα and PI5P4Kβ, respectively. |
M42936 | PBR28 | PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH). |
M42935 | DNA polymerase-IN-4 | DNA polymerase-IN-4, a coumarin derivative, has antiretroviral activity with IC50 value of 134.22 μM. |
M42934 | JH-131e-153 | JH-131e-153, a diacylglycerol (DAG)-lactone, is a small molecule activator of Munc13-1, targeting the C1 domain. |
M42933 | Isoxaben | Isoxaben, a herbicide, inhibits incorporation of radiolabeled glucose into an acid insoluble cell wall fraction. |
M42932 | Triptoquinone H | Triptoquinone H is a class of natural product isolated from traditional Chinese medicine Tripterygium hypoglaucu. |
M42931 | AC-099 hydrochloride | AC-099 hydrochloride is a selective NPFF2R full agonist (EC50=1189 nM) and NPFF1R partial agonist (EC50=2370 nM). |
M42930 | PI5P4Ks-IN-3 | PI5P4Ks-IN-3 is a covalent inhibitor of PI5P4K with IC50s of 1.34 μM (PI5P4Kα), and 9.9 μM (PI5P4Kβ), respectively. |
M42929 | 9-Deazaguanine | 9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP). |
M42928 | Serine Hydrolase inhibitor-21 | Serine Hydrolase inhibitor-21, a pyridine, is a serine hydrolase inhibitor with a Ki of 429 nM for BuChE. |
M42927 | Merodantoin | Merodantoin has significant antitumor activity in vitro and in vivo, and has less toxicity to normal cells and tissues. |
M42926 | Lofepramine | Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. |
M42925 | Cy-FBP/SBPase-IN-1 | Cy-FBP/SBPase-IN-1 is a Cy-FBP/SBPase inhibitor, which is an important regulatory enzyme in cyanobacterial photosynthesis. |
M42924 | XY-52 | XY-52 is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. |
M42923 | AST 7062601 | AST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. |
M42922 | Z-Nle-Lys-Arg-AMC | Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range. |
M42921 | TP-5801 TFA | TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity. |
M42920 | GPR52 receptor modulator 1 | GPR52 receptor modulator 1 (Procedure 1) is a GPR52 receptor modulator with the potential to study neuropsychiatric diseases. |
M42919 | Thozalinone | Thozalinone also known as 5phenyl-2-dimethylamino-2-oxazolin-4-one, is an antidepressant with activity against Tetrabenazine. |
M42918 | 11alpha-Hydroxyprogesterone | 11alpha-Hydroxyprogesterone is the inactive analogue of 11beta-Hydroxyprogesterone, and can be used as an experimental control. |
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