Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M57046 | DL-AP4 | DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. |
M57045 | HPA-12 | HPA-12 is an intracellular ceramide transport protein inhibitor. |
M57044 | ZY-444 | ZY-444 is a small molecule that suppresses breast cancer progression by targeting pyruvate carboxylase. |
M57043 | SBI-477 | SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain–containing 4 (ARRDC4). |
M57041 | AA41612 | AA41612 is a potent antagonist of melanopsin-mediated phototransduction. |
M57040 | UNC7467 | UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. |
M57039 | BLU2864 | BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor (IC50=0.3 nM). |
M57038 | BAY-069 | BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. |
M57037 | MK-6240 | MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs. |
M57036 | LY88074 | LY88074 is a Raloxifene analog lacking the basic side chain. |
M57035 | GSK-114 | GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC50= 25 nM). |
M57034 | RuBiNic | RuBiNic is a cage compound based on the photochemistry of Ru-bpy complexes and releases nicotine by irradiation with visible light up to 532 nm. |
M57033 | HSR6071 | HSR6071, a pyrazinecarboxamide derivative, is an orally active and potent antiallergic agent. |
M57032 | GLPG0259 | GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. |
M57031 | 3BrB-PP1 | 3BrB-PP1 is an ATP-competitive analog. |
M57030 | Kebuzone | Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis. |
M57029 | Pamabrom | Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. |
M57028 | SBP-3264 | SBP-3264 is a valuable chemical probe for understanding the roles of STK3 and STK4 in acute myeloid leukemia (AML). |
M57027 | CGS35066 | CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). |
M57026 | BTB09089 | BTB09089 is a T cell death-associated gene 8 (TDAG8/GPR65) specific agonist. |
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