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Neurotensin Receptor Neurotensin Receptor (NTR)


Cat.No.  Name Information
M11325 AF38469 AF38469 is an orally effective selective Sortilin inhibitor with an IC50 value of 330 nM.
M11312 AF40431 AF40431 is the first reported small molecule ligand of sortilin with IC50 of 4.4 µM and Kd of 0.7 µM. AF40431 binds to the neurotensin binding site of sortilin.
M10571 Neurotensin Neurotensin is a gut tridecapeptide with many central and peripheral functions, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors(NTR).
M7330 Meclinertant Meclinertant (SR 48692) is an effective, selective, non-peptide and oral antagonist of active neurotensin receptor (NTS1). Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization in human colon cancer cells, with a pA2 value of 8.13. Meclinertant has anti-anxiety, anti-addiction and memory disorder effects.

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