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![[Lys8, Lys9]-Neurotensin (8-13) Structure](/upload/structure/139026-64-5.gif)
[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2.
| Molecular Weight | 761 |
| Formula | C38H64N8O8 |
| CAS Number | 139026-64-5 |
| Form | Solid |
| Solubility (25°C) | Water 90 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
| Related Neurotensin Receptor Products |
|---|
| AF38469
AF38469 |
| Meclinertant
Meclinertant (SR 48692) is an effective, selective, non-peptide and oral antagonist of active neurotensin receptor (NTS1). Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization in human colon cancer cells, with a pA2 value of 8.13. Meclinertant has anti-anxiety, anti-addiction and memory disorder effects. |
| SBI-553
SBI-553 is a potent and effective, brain-penetrant and allosteric modulator of NTR1 with EC50 of 0.34 μM. |
| JMV 449 acetate
JMV 449 acetate is a potent neurotensin receptor agonist. |
| Neurotensin
Neurotensin is a gut tridecapeptide with many central and peripheral functions, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors(NTR). |
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