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SBI-553

Cat. No. M10142

All AbMole products are for research use only, cannot be used for human consumption.

SBI-553 Structure
Synonym:

SBI553

Size Price Availability Quantity
1mg USD 70  USD70 In stock
2mg USD 120  USD120 In stock
5mg USD 160  USD160 In stock
10mg USD 230  USD230 In stock
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Quality Control & Documentation
Biological Activity

SBI-553 is a potent and effective, brain-penetrant and allosteric modulator of NTR1 with EC50 of 0.34 μM.

Chemical Information
Molecular Weight 450.55
Formula C26H31FN4O2
CAS Number 1849603-72-0
Solubility (25°C) DMSO 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lauren M Slosky, et al. Trends Pharmacol Sci. Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery

[2] Lauren M Slosky, et al. Cell. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors

[3] Anthony B Pinkerton, et al. J Med Chem. Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators

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Keywords: SBI-553, SBI553 supplier, Neurotensin Receptor, inhibitors, activators

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