Neuropeptide Receptor Neuropeptide receptors

Cat.No.	Name	Information
M9883	CGP 71683A hydrochloride	CGP 71683A hydrochloride is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor with a Ki of 1.3 nM.
M25543	GR231118	GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent, competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8).
M25542	JNJ-5207787	JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50 values of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y1, Y4, and Y5 receptors.
M8432	CYM50769	CYM50769 is a potent, specific antagonist of the Neuropeptide B and Neuropeptide W receptor, NPBWR1 (IC₅₀ = 120 nM).
M7289	SF 11	SF 11 is a nPY Y ₂ receptor antagonist.
M7237	S 25585	S 25585 is a potent and selective NPY Y ₅ receptor antagonist.