Cat.No. | Name | Information |
---|---|---|
M9883 | CGP 71683A hydrochloride | CGP 71683A hydrochloride is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor with a Ki of 1.3 nM. |
M53015 | Pancreatic Polypeptide, bovine | Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion. |
M53014 | Neuropeptide Y (1-24) (human) | Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. |
M53013 | Galanin-Like Peptide (human) | Galanin-Like Peptide (human) is a 60 amino acid neuropeptide. |
M53012 | Neuropeptide SF(mouse, rat) | Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. |
M53011 | Pancreatic Polypeptide, rat | Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4. |
M53010 | Galanin-Like Peptide (rat) | Galanin-Like Peptide (rat) is a 60 amino acid neuropeptide. |
M53009 | Pancreatic polypeptide | Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion. |
M53008 | Ala5-Galanin (2-11) | Ala5-Galanin (2-11) is a galanin receptor 2 (GAL2R) specific agonist with a Ki of 258 nM. |
M53007 | CART (55-76), rat | CART (55-76), rat is a neuropeptide (55-76 residues of the CART peptide) and constitutes the N-terminal fragments of CART (55-102). |
M53006 | Peptide YY (pig) | Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. |
M53005 | AR-M1896 | AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. |
M30680 | RTI-118 | RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration. |
M30138 | Galnon | Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects. |
M30130 | GW438014A | GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents. |
M30096 | NPY5RA-972 | NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor. |
M29873 | Lu AA33810 | Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects. |
M28638 | BIBP3226 | BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect. |
M28094 | Peptide YY (PYY) (3-36), porcine | Peptide YY (PYY) (3-36), porcine is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite. |
M25555 | BIIE-0246 hydrochloride | BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy. |
M25544 | GR231118 TFA | GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent, competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8). |
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