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NPY5RA-972 

Cat. No. M30096

All AbMole products are for research use only, cannot be used for human consumption.

NPY5RA-972  Structure

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Biological Activity

NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor.

Chemical Information
Molecular Weight 351.44
Formula C21H25N3O2
CAS Number 439861-56-0
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] P Li, et al. Int J Obes (Lond). Genetic association analysis of 30 genes related to obesity in a European American population

[2] Bartolo Gabriele, et al. J Org Chem. Efficient synthesis of ureas by direct palladium-catalyzed oxidative carbonylation of amines

[3] Andrew V Turnbull, et al. Diabetes. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats

[4] Michael H Block, et al. J Med Chem. Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity

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Keywords: NPY5RA-972  supplier, Neuropeptide Receptor, inhibitors, activators

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