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Ligands for Target Protein for PROTAC Ligands for Target Protein for PROTAC

Cat.No.  Name Information
M58636 AP1867-2-(carboxymethoxy) AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules.
M58637 PD0325901-O-C2-dioxolane PD0325901-O-C2-dioxolane has main portion of MEK inhibitor PD0325901. PD0325901-O-C2-dioxolane and a ligand of VHL or CRBN E3 ligase can be used in the synthesis of MEK1/2 degrader.
M57131 BTK ligand 1  BTK ligand 1 is a ligand targeting Bruton’s tyrosine kinase (Btk).
M57130 TSPO ligand-1  TSPO ligand-1 is the ligand of AUTAC4 that can be used in the synthesis of PROTACs.
M57129 PROTAC PTK6 ligand-1  PROTAC PTK6 ligand-1 is an intermediate for BTK kinase inhibitor preparation.
M57128 PROTAC BRD4 ligand-2  PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
M57127 Abemaciclib metabolite M18 Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity.
M57126 PROTAC BET-binding moiety 2  PROTAC BET-binding moiety 2 is an inhibitor of BET bromodomain.
M57125 Dasatinib carbaldehyde Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER .
M57124 PROTAC BET-binding moiety 1  PROTAC BET-binding moiety 1 is a key intermediate for the synthesis of high-affinity BET inhibitors.
M57123 PROTAC BRD9-binding moiety 1  PROTAC BRD9-binding moiety 1 is a compound that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.
M57122 Abemaciclib metabolite M18 hydrochloride Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity.
M57121 PROTAC BRD9-binding moiety 1 hydrochloride  PROTAC BRD9-binding moiety 1 hydrochloride is a compound that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.




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