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Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER .
| Molecular Weight | 471.96 |
| Formula | C21H22ClN7O2S |
| CAS Number | 2112837-79-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Ligands for Target Protein for PROTAC Products |
|---|
| BTK ligand 1
BTK ligand 1 is a ligand targeting Bruton’s tyrosine kinase (Btk). |
| TSPO ligand-1
TSPO ligand-1 is the ligand of AUTAC4 that can be used in the synthesis of PROTACs. |
| PROTAC PTK6 ligand-1
PROTAC PTK6 ligand-1 is an intermediate for BTK kinase inhibitor preparation. |
| PROTAC BRD4 ligand-2
PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718. |
| Abemaciclib metabolite M18
Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity. |
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