| Cat.No. | Name | Information |
|---|---|---|
| M5430 | Atorvastatin hemicalcium | Atorvastatin hemicalcium (CI-981) is an orally active inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. |
| M2956 | Pravastatin sodium | Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM. |
| M2283 | Rosuvastatin calcium | Rosuvastatin (Crestor) is a member of statins and used to treat high cholesterol and related conditions. |
| M2126 | Fluvastatin sodium | Fluvastatin sodium is an orally active, potent and competitive HMG-CoA reductase inhibitor with IC50 value between 40 and 100 nM at human liver microsomes. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. |
| M1575 | Lovastatin | Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). |
| M45124 | Fluvastatin | Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway. |
| M40866 | Meglutol | Meglutol is an antilipidemic agent that lowers cholesterol, triglycerides, serum beta-lipoproteins, and phospholipids, and inhibits the activity of the rate-limiting enzyme of cholesterol biosynthesis, HMG-CoA reductase. |
| M31158 | 4-Hydroxy atorvastatin calcium salt | 4-Hydroxy atorvastatin calcium salt is the hydroxyl metabolite of Atorvastatin calcium salt, an inhibitor of HMG-CoA reductase that inhibits cholesterol production with an IC50 value of 8 nM. |
| M31157 | 2-Hydroxy atorvastatin calcium salt | 2-Hydroxy atorvastatin calcium salt is the hydroxyl metabolite of Atorvastatin calcium salt, an inhibitor of HMG-CoA reductase that inhibits cholesterol production with an IC50 value of 8 nM. |
| M28512 | Rosuvastatin Sodium | Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. |
| M9116 | Atorvastatin | Atorvastatin is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. |
| M3527 | Clinofibrate | Clinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood. |
| M56702 | Dalvastatin | Dalvastatin (RG-12561) inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis. |
| M56701 | (3S,5R)-Fluvastatin sodium | (3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. |
| M42446 | Pravastatin lactone | Pravastatin lactone is a potent HMG-CoA inhibitor. |
| M42445 | HMG-CoA Reductase-IN-1 | HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. |
| M42444 | Ganomycin I | Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. |
| M42443 | Ganoderenic acid K | Ganoderenic acid K is a natural product, that can be isolated from fruiting bodies of Ganoderma lucidum. |
| M42442 | Bemfivastatin | Bemfivastatin (PPD 10558) is an orally active, HMG-CoA Reductase (HMGCR) inhibitor, also known as Statin. |
| M30577 | Lovastatin hydroxy acid sodium | Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM. |
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