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Lovastatin

Cat. No. M1575

All AbMole products are for research use only, cannot be used for human consumption.

Lovastatin Structure
Synonym:

MK-803; Mevinolin

Size Price Availability Quantity
10mM*1mL in DMSO USD 45  USD45 In stock
5mg USD 20  USD20 In stock
10mg USD 30  USD30 In stock
50mg USD 50  USD50 In stock
100mg USD 76  USD76 In stock
200mg USD 98  USD98 In stock
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Quality Control & Documentation
Biological Activity

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent).

Product Citations
Customer Product Validations & Biological Datas
Source Pak J Pharm Sci (2016). Figure 1. Lovastatin (Abmole Bioscience)
Method HPLC chromatogram
Cell Lines
Concentrations 200μg/ml
Incubation Time
Results The results summarized in (table 1) obtained for pravastatin, rosuvastatin, pitavastatin, atorvastatin, fluvastatin, lovastatin and simvastatin were comparable with the corresponding labeled amounts.
Chemical Information
Molecular Weight 404.54
Formula C24H36O5
CAS Number 75330-75-5
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nazish Sayed, et al. Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

[2] Yaru Zhang, et al. An overview on the biosynthesis and metabolic regulation of monacolin K/lovastatin

[3] Zixiao Xiong, et al. An overview of the bioactivity of monacolin K / lovastatin

[4] Kelly C L Mulder, et al. Lovastatin production: From molecular basis to industrial process optimization

[5] F P Zeller, et al. Lovastatin for hypercholesterolemia

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  Catalog
Abmole Inhibitor Catalog




Keywords: Lovastatin, MK-803; Mevinolin supplier, HMG-CoA Reductase, inhibitors, activators

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