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HCN Channel Hyperpolarization- and Cyclic Nucleotide-gated (HCN)

Inhibitor

Cat.No.  Name Information
M6063 Zatebradine Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
M5079 Zatebradine hydrochloride Zatebradine(UL-FS49) is a highly effective HCN ion channel antagonist, which can reversively reduce heart rate and inhibit hHCN1 up to 92% at 10uM concentration.
M4976 Ivabradine Ivabradine is a novel medicine indicated for the symptomatic management of stable angina pectoralis.
M45262 KIO-301 KIO-301 a photoswitchable HCN channel blocker, and dihydroorotic acid ester dehydrogenase (DHODH) inhibitor for studies related to ocular diseases.
M30867 BPU-11  BPU-11 is a hyperpolarization-activated cyclic nucleotide-gated (HCN) C-linker pocket (CLP) HCN4 CLP ligand. BPU-11 can be used for the research of congenital immune disease.
M14225 ZD7288 ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
M7768 DK-AH 269 DK-AH 269 (Cilobradine) is an HCN Channel blocker; an open channel blocker of neuronal Ih and related cardiac If channels.




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