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ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
| Molecular Weight | 292.81 |
| CAS Number | 133059-99-1 |
| Solubility (25°C) | DMSO 50 mg/mL Water ≥ 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related HCN Channel Products |
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| RO-275
RO-275 is a potent, selective and orally active HCN1 inhibitor with IC50 values of 0.046, 14.3, 4.6, 13.9 µM for HCN1, HCN2, HCN3, HCN4, respectively. The selective HCN1 inhibitor RO-275 improved performance in a translationally relevant touchscreen task of WM (TUNL) in rats. |
| KIO-301
KIO-301 a photoswitchable HCN channel blocker, and dihydroorotic acid ester dehydrogenase (DHODH) inhibitor for studies related to ocular diseases. |
| BPU-11
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