Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M10346 | Glutamic acid (L-Glutamic acid) | L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| M18309 | p-Hydroxy-cinnamic acid | p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. |
| M6687 | Docosahexaenoic acid (Oil) | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist. |
| M9953 | Taurocholic acid | Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats. |
| M10168 | L-Lactic acid | L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. |
| M39070 | Hydroxytanshinone IIA | Hydroxytanshinone IIA is a hydroxylated metabolite of Tanshinone IIA. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2. |
| M39069 | Desmethyl Levofloxacin | Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
| M39068 | 15-Acetyl-deoxynivalenol | 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells. |
| M39067 | 1-Aminohydantoin hydrochloride | 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. |
| M39066 | Ferulic acid acyl-β-D-glucoside | Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. |
| M39065 | N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide | N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide (Macamide impurity 10) is the impurity of Macamide. |
| M31240 | His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA | His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1 has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels. |
| M30888 | 10-Formyltetrahydrofolic acid disodium | 10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines. |
| M30778 | (R)-Linezolid | (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis. |
| M30729 | Glycocholic acid sodium | Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways. |
| M30438 | Protectin D1 | Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models. |
| M30414 | 4'-Hydroxy diclofenac | 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. |
| M30413 | Diclofenac acyl glucuronide | Diclofenac acyl glucuronide (D-1-O-G) is a major bile metabolite directly involved in small intestinal ulceration in rats. |
| M30380 | α-Viniferin | α-Viniferin is an anti-inflammatory compound from Caragana chamlagu root. |
| M30311 | (±)-Nornicotine | (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health. |
| M30238 | Adrenaline sulfate | Adrenaline sulfate is a orally active hormone secreted by the medulla of the adrenal glands. Adrenaline sulfate is an α-adrenergic and β-adrenergic receptor agonist. Adrenaline sulfate can be used in the research of anaphylaxis. Adrenaline sulfate has the potential for the research of cardiac arrest. |
| M30204 | NAPQI | NAPQI is the toxic metabolite of Acetaminophen. NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver. |
| M30176 | (R)-Pantetheine | (R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA). |
| M30169 | Dehydroascorbic acid | Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. |
| M30144 | Isotetrandrine | Isotetrandrine is a bioactive component in Stephania tetrandra. |
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