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CRFR CRFR

Cat.No.  Name Information
M6198 Verucerfont Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively.
M54655 K41498 TFA K41498 TFA is an antisauvagine-30 (aSvg-30) analog and a strongly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM, and 425 nM for human CRF2α, CRF2β, and CRF1 receptors, respectively.K41498 TFA inhibits sauvagine-stimulated cAMP accumulation in hCRF2α/hCRF2β expressing cells. K41498 TFA can be used in hypotension studies.
M54646 Astressin 2B TFA Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist with IC50 values of 1.3 and > 500 nM for CRF2 and CRF1, respectively.
M10333 CRF (bovine) TFA CRF (bovine) TFA is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
M9705 CP-376395 CP-376395 is a CRF1-selective antagonist.
M54394 Urocortin, rat Urocortin, rat (Urocortin (Rattus norvegicus)) is a neuropeptide and a potent endogenous CRFR agonist with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively.
M54287 Urocortin, human Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively.
M54112 CRF(6-33)(human) CRF(6-33)(human) is a CRF binding protein (CRF-BP) ligand inhibitor.
M54012 α-Helical CRF(9-41) α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM.
M53221 (D-Phe12, Nle21, 38, α-Me-Leu37)-CRF (12-41) (human, rat) (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist.
M53220 Urocortin III, mouse Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide.
M53219 Sauvagine Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist.
M53218 a-Helical Corticotropin Releasing Factor (9-41) α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist.
M53217 [DPro5] Corticotropin Releasing Factor, human, rat [DPro5] Corticotropin Releasing Factor, human, rat is a selective R2 agonist of corticotropin releasing factor/hormone.
M53216 (Tyr0)-Urocortin, rat (Tyr0)-Urocortin, rat is a high-affinity agonist of corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2).
M53215 a-Helical Corticotropin Releasing Factor (12-41) a-Helical Corticotropin Releasing Factor (12-41) is a 30 amino acids long, α-helical analogue of corticotropin releasing factor/hormone.
M53214 Stresscopin-related peptide (human) Stresscopin-related peptide (human) is a specific ligand for the type 2 CRH receptor.
M53213 Urocortin III (human) Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide.
M53212 Urocortin II, human Urocortin II (human) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor.
M53211 Urocortin II, mouse Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively.




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