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CRFR CRFR

Cat.No.  Name Information
M6198 Verucerfont Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively.
M53217 [DPro5] Corticotropin Releasing Factor, human, rat [DPro5] Corticotropin Releasing Factor, human, rat is a selective R2 agonist of corticotropin releasing factor/hormone.
M53216 (Tyr0)-Urocortin, rat (Tyr0)-Urocortin, rat is a high-affinity agonist of corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2).
M53215 a-Helical Corticotropin Releasing Factor (12-41) a-Helical Corticotropin Releasing Factor (12-41) is a 30 amino acids long, α-helical analogue of corticotropin releasing factor/hormone.
M53214 Stresscopin-related peptide (human) Stresscopin-related peptide (human) is a specific ligand for the type 2 CRH receptor.
M53213 Urocortin III (human) Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide.
M53212 Urocortin II, human Urocortin II (human) is a selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor.
M53211 Urocortin II, mouse Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively.
M53210 CRF, bovine CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
M53209 Urotensin I Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, respectively.
M40826 Crinecerfont Crinecerfont is a potent, orally active, specific nonpeptide corticotropin-releasing factor 1 receptor (CRF1) antagonist for studies related to congenital adrenal hyperplasia (CAH).
M30116 Pexacerfont Pexacerfont is a selective corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1±0.6 nM for human CRF1 receptor.
M29045 R121919 R121919 (NBI30775) is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
M27639 Tildacerfont  Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia.
M13937 Corticotropin-releasing factor (human) (acetate) Corticotropin-releasing factor human acetate (Human CRF acetate) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
M13936 Corticotropin-releasing factor (human) Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.




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