| Cat.No. | Name | Information |
|---|---|---|
| M1973 | Ostarine (MK-2866) | Ostarine (GTx-024 and MK-2866) is an investigational selective androgen receptor modulator (SARM) with Ki of 3.8 nM. |
| M6033 | Dihydrotestosterone | Dihydrotestosterone is an androgen (male hormone). Specifically it's the strongest of the androgens. It can be used to construct animal models of polycystic ovary syndrome (PCOS). |
| M6105 | Testosterone | Testosterone is an androgen, which binds the androgen receptor. |
| M5565 | Dexmedetomidine HCl | Dexmedetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. |
| M5805 | Nandrolone | Nandrolone is a synthetic, anabolic steroid analog of testosterone. |
| M1839 | MDV3100 | MDV3100 is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. |
| M5764 | Medroxyprogesterone acetate | Medroxyprogesterone acetate (MPA) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding. |
| M2270 | Apalutamide (ARN-509) | Apalutamide (ARN-509) is a novel androgen receptor (AR) antagonist for the treatment of castration-resistant prostate cancer (CRPC). |
| M10306 | Bavdegalutamide (ARV-110) | Bavdegalutamide (ARV-110) is an oral, specific androgen receptor (AR) PROTAC degrader. |
| M43587 | Androgen receptor degrader-2 | Androgen receptor degrader-2 is a potent androgen receptor degrader. |
| M43586 | Androgen receptor degrader-1 | Androgen receptor degrader-1 is a potent androgen receptor degrader. |
| M43585 | WCA-814 | WCA-814 is an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate. |
| M43584 | Androgen receptor antagonist 8 | Androgen receptor antagonist 8 is an androgen receptor antagonist. |
| M43583 | JNJ-26146900 | JNJ-26146900 is a potent and orally active androgen receptor antagonist with a Ki value of 400nM for rat AR. |
| M43582 | JJH260 | JJH260 is AIG1 inhibitor, and inhibit the fluorophosphonate reactivity and fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1in HEK293T cells. |
| M40985 | LPCN 1144 | LPCN 1144 is an androgen receptor (AR) agonist that may be used in studies related to non-alcoholic steatohepatitis (NASH). |
| M39856 | Linuron | Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor. |
| M39855 | Galloylalbiflorin | Galloylalbiflorin (6′-O-Galloylalbiflorin) is an androgen receptor (AR) antagonist (IC50=53.3 μM) and can be found in the roots of Paeonia lactiflora. Galloylalbiflorin shows anti-androgens activity. |
| M30724 | AH3960 | AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1). |
| M30623 | MK-4541 | MK-4541 is an orally active and selective androgen receptor (AR) modulator. MK-4541 acts as an antagonist to inhibit 5α-reductase. MK-4541 inhibits proliferation and induces apoptosis in AR positive prostate cancer cells. MK-4541 significantly inhibited the growth of R3327-G prostate tumors in xenograft mouse model. |
| M29958 | AR antagonist 3 | AR antagonist 3 is a potent and selective androgen receptor (AR) antagonist with an IC50 of 0.47 µM. AR antagonist 3 exhibits a dose-dependent decrease of the FRET signal (IC50= 18.05 μM). AR antagonist 3 shows effective inhibition on tumor growth when administered intratumorally. |
| M29728 | Topilutamide | Topilutamide is a topical nonsteroidal antiandrogen (NSAA). |
| M29505 | ARD-69 | ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression. |
| M29317 | UT-34 | UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy. |
| M29293 | EPI-7170 | EPI-7170, a ralaniten analogue, is a potent androgen receptor N-terminal structural domain antagonist that blocks the transcriptional activity of full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170 has antitumor effects against enzalutamide resistant castration-resistant prostate cancer (CRPC). |
| M29251 | JNJ-63576253 free base | JNJ-63576253 (TRC-253) free base is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 free base can be used for the research of castration-resistant prostate cancer (CRPC). |
| M29116 | (R)-UT-155 | (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer. |
| M28937 | Gumelutamide | Gumelutamide is a tetrahydropyridopyrimidine compound, acting as an antiandrogen, antineoplastic agent. Gumelutamide is an androgen antagonist. |
| M28761 | ODM-204 | ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80 nM and 22 nM, respectively. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
