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S-23

Cat. No. M14621

All AbMole products are for research use only, cannot be used for human consumption.

S-23 Structure

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Quality Control & Documentation
Biological Activity

S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.

Chemical Information
Molecular Weight 416.75
CAS Number 1010396-29-8
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alice Ameline, et al. In vitro characterization of S-23 metabolites produced by human liver microsomes, and subsequent application to urine after a controlled oral administration

[2] Katy Daz, et al. Exogenous Application of Brassinosteroid 24-Norcholane 22( S)-23-Dihydroxy Type Analogs to Enhance Water Deficit Stress Tolerance in Arabidopsis thaliana

[3] Yat-Ming So, et al. Metabolic studies of selective androgen receptor modulators RAD140 and S-23 in horses

[4] Philipp Stegmeier, et al. Thrombocytopenia after implantation of the Perceval S aortic bioprosthesis

[5] O Boutaud, et al. Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase

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  Catalog
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Keywords: S-23 supplier, Androgen Receptor, inhibitors, activators

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