Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
M21586 | Poly(2-hydroxyethyl methacrylate) (MW 1000000) | Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials field. Poly(2-hydroxyethyl methacrylate) serves as the basic component of contact lenses, and is also used for soft tissue implantation, synthetic transplantation of carwrist and bone, regeneration of nervous system tissues, compound delivery, etc. |
M21585 | Poly(2-hydroxyethyl methacrylate) (MW 20000) | Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials field. Poly(2-hydroxyethyl methacrylate) serves as the basic component of contact lenses, and is also used for soft tissue implantation, synthetic transplantation of carwrist and bone, regeneration of nervous system tissues, compound delivery, etc. |
M21582 | L-Glucose | L-glucose (L-(-) -glucose) is an enantiomer of D-glucose. L-Glucose enhances food intake, and cells can't use it as an energy source because it can't be phosphorylated by hexokinase. |
M21569 | Diethyl succinate | Diethyl succinate (Diethyl Butanedioate) is the Diethyl form of succinate. Diethyl succinate (Diethyl Butanedioate) can be used at physiological pH and passed through a biofilm. Incorporated into cells in tissue cultures and metabolized through the TCA cycle. Diethyl succinate was not toxic. |
M21563 | Ethoxylated hydrogenated castor oil | Ethoxylated castor oil (PEG-40 hydrogenated castor oil) is a mixture of polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used for emulsification and solubility of oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a co-solvent for animal experiments. |
M21562 | Zymosan A from Saccharomyces cerevisiae | Zymosan A can increase the level of cyclin D2, suggesting the role of cyclin D2 in macrophage activation and proliferation. After injection of galactosamine, it aggravated acute liver injury, suggesting that some non-parenchymal cells besides Kupfer's cells were involved in fermentase action. |
M21553 | Poly-L-lysine (MW 4000~15000) | Poly-L-lysine |
M21544 | 4-Biphenylboronic acid | 4-Biphenylboronic acid is a boric acid compound. |
M21542 | Deoxyribonucleic acid sodium salt from salmon testes | Salmon refined deoxyribonucleic acid (SS-DNA) can be used to study the physical and chemical interactions of DNA with binders, inserters, modifiers, detection agents and densifiers. Salmon extract DNA was used to investigate the loading capacity of magnetic mesoporous silica nanoparticles (M-MSNs) and the bonding capacity of polymer nanolayer structures. SS-DNA can be used as a substrate for developing DNA detection methods. |
M21541 | L-2-Aminooxy-3-phenylpropanoic acid | L-2-Aminooxy-3-phenylpropanoic acid is an inhibitor of L-phenylalanine ammonia-lyase. |
M21538 | Diphenyl diselenide | Diphenyl diselenide inhibits δ-aminolevulinic acid dehydrase (δ-ALA-D) in brain, liver, and kidney in vivo. Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction. |
M21528 | 1-Carbamoylcyclopropanecarboxylic acid | |
M21511 | RGLS4326 | RGLS4326 (RG4326) is a first-in-class microRNA-17 (miR-17) oligonucleotide inhibitor. RGLS4326 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 acts on HeLa cells to inhibit the function of miR-17 with EC50 value of 28.3 nM. |
M21499 | Rodatristat ethyl | Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity. |
M21497 | Gemcabene calcium | Gemcabene calcium (PD-72953 calcium), the pioneering (first-in-class) lipid-lowering agent, can lower density lipoprotein cholesterol (LDL-C), lower triglycerides, and increase high-density lipoprotein cholesterol (HDL-C), and lower pro-inflammatory acute phase proteins. C-reactive protein (CRP), which shows anti-inflammatory activity. |
M21492 | Omadacycline | Omadacycline (PTK 0796) tosylate, the first (first-in-class) orally active aminomethylcycline antibiotic, is a tetracycline antibiotic. Omadacycline tosylate can be used to study acute bacterial skin and skin structure infections, infectious pneumonia, and urinary tract infections. |
M21473 | Padsevonil | Padsevonil (UCB0942) is the first effective antiepileptic agent. Padsevonil can be used in the study of epilepsy. |
M21472 | Gemcabene | Gemcabene (PD-72953) is a first-in-class PPARα agonist, lipid-lowering agent. It lowers density lipoprotein cholesterol (LDL-C), lowers triglycerides and increases high density lipoprotein cholesterol (HDL-C), and lowers the pro-inflammatory acute phase protein, C-reactive protein (CRP), showing anti-inflammatory activity. |
M21462 | 24-Norursodeoxycholic acid | 24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties. |
M21454 | Cyclohexanecarboxamide | Cyclohexanecarboxamide is a useful chemical for research. |
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