| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M21439 | Poly-D-lysine hydrobromide (70,000-150,000) | Poly-D-lysine hydrobromide (70,000-150,000) |
| M21432 | Hyaluronic Acid (10K) | Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. |
| M21361 | Tetramethyluric Acid | Tetramethyluric Acid is a purine alkaloid found in the leaves of wild bitter tea (Camellia kucha Hung T. Chang) with a molecular structure that has one more methyl group than the caffeine commonly found in tea leaves. |
| M21351 | 2-Benzylsuccinic acid | 2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a potent inhibitor of carboxypeptidase A (CPA). |
| M21339 | 2-(Chloromethyl)benzoic acid | 2-Chloromethylbenzoic Acid acts as a reagent for the synthesis of (azolyl)methyl)arylbenzamides as dual inhibitors of VEGFR-1/2 kinases. |
| M21334 | 1-3-Dimethylaminopropyl-3-ethylcarbodiimide | N-(3-dimethylaminopropyl)-N′-ethylcarbonyldiamine and N-hydroxysuccinimide (NHS) are often used together to activate the carbonyl group in carbodiimide coupling reactions and to couple with the amine to form amides. |
| M21333 | 11-Mercaptoundecanoic acid | 11-Mercaptoundecanoic acid (MUA), a thiol-containing fatty acid used to design monolayers, has been used to prepare self-assembled monolayers (SAMs), hybrid monolayers, and metal-conjugated nanoparticles. |
| M21304 | Thiobarbituric acid | Thiobarbituric acid has antibacterial activity. |
| M21282 | BI-0115 | BI-0115 inhibits the C-type lectin family member lectin-like oxidized LDL-receptor-1 (LOX-1) by stabilizing an inactive tetrameric form of the protein. |
| M21208 | BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. |
| M21152 | SJ6986 | SJ6986 is a potent, selective, and orally effective GSPT1/2 degradation agent with a DC50 value of 2.1 nM (Dmax 99%) for GSPT1. |
| M21103 | Iclepertin | Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS). |
| M21083 | PY-60 | PY-60 is a specific activator (Kd=1.4 µM) of YAP transcriptional activity targeting membrane associated protein A2 (ANXA2).PY-60 binds directly to ANXA2 and antagonizes its normal cellular function of inhibiting YAP activity. |
| M21073 | 4-Deoxypyridoxine hydrochloride | 4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities. |
| M21059 | S-217622 | S-217622 is the first oral, non-covalent, non-peptide inhibitor of SARS-CoV-2 3CL (major protease) (IC50=13 nM). |
| M21017 | Sugammadex sodium | Sugammadex sodium is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery in adults. |
| M21010 | L-carnosine | L-carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress. |
| M21009 | L-Ornithine hydrochloride | L-ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. |
| M21007 | Phytic acid | Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. |
| M20962 | Uridine triacetate | Uridine triacetate is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity. |
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