Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
M20893 | Tyramine | Tyramine is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent. |
M20891 | Grape Seed Extract | Grape Seed Extract are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid, and OPCs. |
M20855 | Guanethidine Monosulfate | Guanethidine monosulfate is an antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. |
M20843 | NNMTi | NNMTi (Compound 1k, NNMT inhibitor) is a potent nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 1.2 μM. |
M20837 | Simufilam dihydrochloride | Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies. |
M20831 | SGN-2FF | SGN‐2FF (2-fluorofucose) is an orally bioavailable small‐molecule inhibitor of fucosyltransferase that demonstrated encouraging preclinical antitumor activity in mouse models. |
M20821 | Gap19 TFA | Gap19 TFA is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary. |
M20716 | MBP146-78 | MBP146-78 is a potent and selective inhibitor of cyclic GMP(cGMP)-dependent protein kinases/Protein Kinase G (PKG) and displays cytostatic activity against Toxoplasma gondii. |
M20681 | Sphingosine | Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid. |
M20626 | Amcasertib (BBI503) | Amcasertib (BBI-503) is an oral first-in-class cancer stemness kinase inhibitor. By targeting multiple serine-threonine stemness kinases, amcasertib inhibits Nanog and other cancer stemness pathways. |
M20570 | Ufiprazole | Ufiprazole (Omeprazole sulfide) is an intermediate used in the production of the gastric proton pump inhibitors omeprazole and esomeprazole. |
M20565 | Tricarballylic acid | Tricarballylic acid is an inhibitor of aconitase and therefore interferes with the Krebs cycle. |
M20540 | Alrestatin | Alrestatin is an inhibitor of aldose reductase which is involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy. |
M20513 | Hydroxyzine pamoate | Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probably effective in the treatment of insomnia and withdrawal treatment. |
M20464 | Atrazine | Atrazine is a selective triazine herbicide. Atrazine is also a potent endocrine disruptor that is active at low, ecologically relevant concentrations. |
M20445 | Indometacin Sodium | Indometacin is a non-steroidal anti-inflammatory drug (NSAID) used most commonly for the treatment of inflammation and pain resulting from rheumatic disease (arthritis), and less commonly in postoperative pain management. When taken for chronic pain conditions, indometacin has been associated with a high incidence of adverse events. The benefits and harms of orally-administered indometacin for postoperative pain are not clear. |
M20182 | WAY-600704 | WAY-600704 is a ethanolamine kinase inhibitor. |
M20094 | WAY-321366 | WAY-321366 is a abelson tyrosine kinase inhibitor |
M20008 | N-Acetyl-DL-aspartic acid | N-Acetyl-DL-aspartic acid |
M20004 | Protoporphyrin IX cobalt chloride | Protoporphyrin IX cobalt chloride (CoPP) is a potent HO-1 inducer. |
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