| Cat.No. | Name | Information |
|---|---|---|
| M1966 | Fulvestrant | Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. |
| M3371 | Estriol | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
| M4368 | Kaempferol | Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. |
| M7353 | Tamoxifen | Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. |
| M7871 | G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. |
| M4374 | Gypenoside-XVII | Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. |
| M2174 | Calcitriol | Calcitriol is an Active metabolite of vitamin D3 that activates the vitamin D receptor. *The compound is unstable in solutions, freshly prepared is recommended |
| M4836 | G-1 | G-1 is a potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM). |
| M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
| M10348 | 27-Hydroxycholesterol | 27-Hydroxycholesterol is a selective estrogen receptor modulator, and it is also an agonist of the liver X receptor. |
| M28294 | (R,R)-THC | (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6. |
| M27905 | DK3 | DK3 is a potent and selective estrogen-related receptor alpha (ERRα) agonist. |
| M24864 | Corifollitropin alfa | Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility. |
| M22285 | Endoxifen hydrochloride | Endoxifen hydrochloride is a key active metabolite of Tamoxifen and an estrogen receptor (ER) modulator with high affinity and specificity for the estrogen receptor and inhibits aromatase activity.Endoxifen hydrochloride has been used in studies related to breast cancer, sclerofibroblastoma, and bipolar disorder. Research. |
| M21273 | GNE-149 | GNE-149 is an efficient monovalent degrader and full antagonist of estrogen receptor alpha with significant oral bioavailability in higher species. |
| M20990 | Norethindrone acetate | Norethindrone acetate (19-Norethindrone acetate, NA) is a common synthetic hormone used in oral contraceptives. Norethindrone acetate is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis. |
| M20989 | Megestrol | Megestrol, a synthetic progestin, is approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis. Megestrol acetate (Megace) is one of the first progestational agents to be evaluated for use in the hormonal therapy of advanced breast cancer. |
| M20941 | Raloxifene | Raloxifene is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. |
| M20905 | Lynestrenol | Lynestrenol is a synthetic progestational hormone, an agonist of the progesterone receptor and has weak androgenic and estrogenic activity. |
| M20894 | Promestriene | Promestriene (3-propyl ethyl, 17B-methyl estradiol) is a synthetic estrogen analog that has been reported to significantly improve the symptoms of vaginal atrophy caused by estrogen deprivation in topical application. |
| M20639 | H3B-5942 | H3B-5942 is a selective and irreversible estrogen receptor covalent antagonist, inactivates both ERα WT and ERα mutation. The Ki values are 1 nM and 0.41 nM, respectively. |
| M20545 | 17-Beta-Estradiol-3,17-Dipropionate | Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a semisynthetic, steroidal estrogen which has been used in hormone therapy for menopausal symptoms and low estrogen levels in women and in the treatment of gynecological disorders. |
| M20488 | 4,4'-DDE | DDE, a breakdown product of DDT, is an organochlorine pesticide and may behave as a potent androgen receptor antagonist. |
| M14632 | H3B-6545 hydrochloride | H3B-6545 hydrochloride is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. |
| M14631 | H3B-6545 | H3B-6545 is an oral, selective estrogen receptor covalent antagonist (SERCA) for the research of metastatic ER-positive, HER2-negative breast cancer. |
| M14630 | Enclomiphene citrate | Enclomiphene citrate is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property. |
| M14627 | Droloxifene | Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. |
| M14625 | AZD9496 maleate | AZD9496 maleate is a potent and selective estrogen receptor (ERα) antagonist with IC50 of 0.28 nM. AZD9496 maleate is an orally bioavailable selective oestrogen receptor degrader (SERD). |
| M10910 | Zuclomiphene citrate | Zuclomiphene citrate is a cis isomer of clomiphene citrate. Zuclomiphene citrate has an anti-estrogen effect and inhibits the secretion of luteinizing hormone (LH) more than trans isomers. Zuclomiphene citrate is also an oral active cholesterol lowering agent. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
