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Cat. No. M4368
Kaempferol Structure

Robigenin; Kempferol

Size Price Availability Quantity
25mg USD 31.5  USD35 In stock
50mg USD 40.5  USD45 In stock
100mg USD 74.7  USD83 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Kaempferol inhibits topoisomerase I catalyzed DNA religation and may also inhibit the activity of fatty acid synthase.

Product Citations
Customer Product Validations & Biological Datas
Source J Cell Mol Med 2020 May. Figure 8. Kaempferol (Abmole Bioscience, USA)
Method HPLC-MS
Cell Lines -
Concentrations -
Incubation Time -
Results Kaempferol interacts with 3 amino acids, ARG 288, LEU 330 and SER 342, near the PPARγ active site and forms 4 hydrogen bonds, thus promoting binding. Naringenin formed a network of five hydrogen bonds with PPARγ through 4 amino acids, CYS 285, HIS 440, TYR 327 and LEU 340, near the active site, establishing stable binding
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 286.23
Formula C15H10O6
CAS Number 520-18-3
Purity >98%
Solubility DMSO: ≥ 30 mg/mL
Storage at -20°C

A network pharmacology-based approach to explore the effects of Chaihu Shugan powder on a non-alcoholic fatty liver rat model through nuclear receptors
Huan Nie, et al. J Cell Mol Med. 2020 May;24(9):5168-5184. PMID: 32189432.

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Keywords: Kaempferol, Robigenin; Kempferol supplier, Estrogen Receptor, inhibitors

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