Cat.No. | Name | Information |
---|---|---|
M1966 | Fulvestrant | Fulvestrant is a Estrogen receptor (ER) antagonist with IC50 of 0.094 nM. Fulvestrant can also induce autophagy and apoptosis, and has anti-tumor effect. |
M3371 | Estriol | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. |
M4368 | Kaempferol | Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research. |
M7353 | Tamoxifen | Tamoxifen is a estrogen receptor partial agonist/antagonist. |
M7871 | G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM. |
M4374 | Gypenoside-XVII | Gypenoside XVII is a novel phytoestrogens belonging to gypenosides, which can activate estrogen receptors. |
M2174 | Calcitriol | Calcitriol is an Active metabolite of vitamin D3 that activates the vitamin D receptor. *The compound is unstable in solutions, freshly prepared is recommended |
M4836 | G-1 | G-1 is a potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM). |
M8508 | PHTPP | PHTPP is a selective estrogen receptor β (ERβ) full antagonist with 36-fold selectivity for ERβ over ERα. |
M10348 | 27-Hydroxycholesterol | 27-Hydroxycholesterol is a selective estrogen receptor modulator, and it is also an agonist of the liver X receptor. |
M7493 | XCT 790 | XCT 790 is a potent, selective ERRα inverse agonist with an IC50 value of 0.37 μM and is inactive against ERRγ and estrogen receptors ERα and ERβ. |
M7483 | WAY 200070 | WAY 200070 is a selective ERβ agonist. |
M6717 | ERB 041 | ERB 041 is a potent and selective estrogen receptor β (ERβ) agonist, with IC50s of 5.4, 3.1, and 3.7 nM for ERβ in humans, rats, and mice, respectively.ERB 041 is more than 200 times more selective for ERβ than for ERα. In addition, ERB 041 inhibits the WNT/β-catenin signaling pathway and induces apoptosis in ovarian cancer cells. |
M6710 | Endoxifen Z-isomer hydrochloride | Endoxifen Z-isomer hydrochloride is a Tamoxifen metabolite and a potent estrogen receptor (ER) antagonist that concentration-dependently inhibits hERG with an IC50 value of 1.6 μM. |
M6165 | GSK 4716 | GSK 4716 is a selective agonist with estrogen-related receptors ERRβ and ERRγ. |
M6083 | AZD9496 | AZD9496 is an oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models. |
M6069 | β-Estradiol 17-acetate | β-Estradiol 17-acetate is a metabolite of estradiol. |
M5917 | Raloxifene HCl | RaloxifeneHcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist. |
M5765 | Megestrol Acetate | Megestrol acetate is a synthetic progestogen, used to treat breast cancer and loss of appetite. |
M5698 | Hydroxyprogesterone caproate | Hydroxyprogesterone Caproate is a synthetic progesterone receptor (PR) agonist that binds and activates the nuclear progesterone receptor in the reproductive system and may be used in studies related to genitourinary disorders. |
M5668 | Bavachin | Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively. |
M5635 | Etonogestrel | Etonogestrel is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. |
M5628 | Ethisterone | Ethisterone is a progestogen hormone being considered to treat prostate cancer. |
M5627 | Estropipate | Estropipate is a form of estrogen, used to treat symptoms of menopause, also used to prevent osteoporosis. |
M5599 | Drospirenone | Drospirenone is a synthetic progestin that is an analog to spironolactone. |
M5564 | Desogestrel | Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents. |
M5511 | Chlormadinone acetate | Chlormadinone acetate is a steroidal progestin with additional antiandrogen and antigonadotropic effects, used often in combinations as an oral contraceptive. Its half-life is about 34-38 hours. |
M5434 | Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. |
M4835 | DPN | DPN is a highly potent estrogen ERβ receptor agonist with a 70-fold selectivity over ERα with EC50 values are 0.85 and 66 nM,respectively. |
M4834 | Propyl pyrazole triol (PPT) | PPT is a potent subtype-selective estrogen receptor agonist with EC50 ~ 200 pM and displays 410-fold selectivity for ERα over ERβ. |
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