About 6 results found for searched term "YL-109" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9490 | YL-109 | Aryl hydrocarbon Receptor |
| YL-109 is a novel anticancer agent, which can inhibit breast cancer cell growth and invasiveness in vitro and in vivo, YL-109 is also an STUB1 enhancer. | ||
| M3953 | Voriconazole | Cytochrome P450 (e.g. CYP17) |
| UK-109496 | ||
| Voriconazole (UK-109496) is an inhibitor of 14α-lanosterol demethylase with IC50 value of 53 nM. Voriconazole (UK-109496) is also a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. | ||
| M29902 | Gatifloxacin mesylate | Antibiotic |
| AM-1155 mesylate; BMS-206584 mesylate; PD135432 mesylate | ||
| Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). | ||
| M40637 | TD-1092 | IAP |
| TD-1092 is a pan-inhibitor of apoptosis (IAP) degrader with two different types of E3 ligase conjugates, IAP and CRBN, that induces proteasomal degradation of cIAP2 and XIAP in a CRBN-dependent manner. TD1092 also activates apoptotic proteases (apoptosis 3/7) and leads to apoptosis by promoting IAP degradation. In addition, TD1092 also blocks the TNFα-mediated NF-κB signaling pathway and inhibits the phosphorylation of IKK, IkBα, p65, and p38. TD1092 can be used as a PROTAC for cancer research. | ||
| M42364 | N-methyl-N-dithiocarboxyglucamine sodium | Metabolite/Endogenous Metabolite |
| N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound 109Cd in mouse model. | ||
| M54846 | Tacrine | AChR/AChE |
| 1,2,3,4-Tetrahydroacridin-9-amine | ||
| Tacrine is a potent acetylcholinesterse (AChE) inhibitor (IC50=109 nM), also acting as a CYP1A2 substrate agent. | ||
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