All AbMole products are for research use only, cannot be used for human consumption.
Voriconazole (UK-109496) is an antifungal compound used to treat severe fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase, leading to ergosterol depletion in fungal cell membranes. Voriconazole is widely metabolized in the liver by the cytochrome P450 enzyme, mainly CYP2C9 and CYP3A4.
| Molecular Weight | 349.32 |
| Formula | C16H14F3N5O |
| CAS Number | 137234-62-9 |
| Solubility (25°C) | DMSO 60 mg/mL Ethanol 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Cytochrome P450 (e.g. CYP17) Products |
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| Musk ketone
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. |
| MS-PPOH
MS-PPOH is a potent and selective cytochrome P450 (CYP) epoxygenase inhibitor. |
| (R)-Mephenytoin
(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. |
| (3S,5S)-Atorvastatin
(3S,5S)-Atorvastatin is a inactive enantiomer of Atorvastatin. |
| (3S,5S)-Atorvastatin sodium salt
(3S,5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. |
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