About 14 results found for searched term "VT5" (0.059 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13341 | VTP50469 | Histone Methyltransferase |
| VTP50469 is a potent, highly selective and orally active inhibitor of Menin-MLL Interaction with a Ki value of 104 pM. VTP50469 has anti-leukemia activity. | ||
| M5922 | Ranolazine | Calcium Channel |
| CVT 303, RS 43285-003 | ||
| Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). | ||
| M6153 | E6005 | PDE |
| RVT-501 | ||
| RVT-501 (E6005) is a selective phosphodiesterase 4 (PDE4PDE4) inhibitor with an IC50 of 2.8 nM. | ||
| M13429 | VTP50469 fumarate | Epigenetic Reader Domain |
| VTP50469 fumarate is a Menin-MLL interaction inhibitor with a Ki of 104 pM. Effective against MLL rearrangement and NPM1c+ leukemia. It has effective anti-leukemia activity. | ||
| M14664 | BVT-14225 | Hydroxysteroid dehydrogenase |
| BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM. | ||
| M25154 | Quisovalimab | Anti-infection |
| AVTX-002; AEVI 002; SAR 252067 | ||
| Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) COVID-19. Quisovalimab can be used in COVID-19 acute respiratory distress syndrome and other studies. | ||
| M25230 | Urtoxazumab | Others |
| HuVTm1.1 TMA-15 | ||
| Urtoxazumab (TMA-15) is a humanized monoclonal antibody against Shiga toxin (Stx) 2. | ||
| M29191 | VT-1598 | Antifungal |
| VT-1598 is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris. | ||
| M29192 | VT-1598 tosylate | Cytochrome P450 (e.g. CYP17) |
| VT-1598 tosylate is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 tosylate shows anti-fungal activity against C. auris. | ||
| M31263 | VT02956 | YAP |
| VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1, 0.52 nM for LATS2). VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and tumor organoids. | ||
| M40834 | VTX-958 | JAK |
| VTX-958 is an allosteric TYK2 inhibitor that can be used in studies related to psoriasis. | ||
| M45277 | VTX-2735 | NLR |
| VTX-2735 is an NLRP3 inhibitor that can be used in studies related to inflammatory diseases. | ||
| M51498 | VT5 | Others |
| VT5 is a β-sheet amphipathic peptide consisting of 26 amino acids. | ||
| M54688 | Pegtibatinase | Others |
| OT-58; TVT-58 | ||
| Pegtibatinase is a cystathionine beta synthase (CBS) regulator that can be used in studies related to homocystinuria. | ||
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