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VT-1598

Cat. No. M29191

All AbMole products are for research use only, cannot be used for human consumption.

VT-1598 Structure

Size	Price	Availability	Quantity
5mg	USD 380 USD380	In stock
10mg	USD 560 USD560	In stock
25mg	USD 900 USD900	In stock
50mg	USD 1400 USD1400	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation

Purity: ≥99.0%
COA
MSDS

Product Information

Biological Activity

VT-1598 is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris.

Chemical Information

Molecular Weight	584.52
Formula	C31H20F4N6O2
CAS Number	2089320-99-8
Form	Solid
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Samantha E Jacobs, et al. F1000Res. Novel antifungal agents in clinical trials

[2] E P Garvey, et al. Med Mycol. The novel fungal CYP51 inhibitor VT-1598 displays classic dose-dependent antifungal activity in murine models of invasive aspergillosis

[3] Nathan P Wiederhold, et al. Antimicrob Agents Chemother. The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates In Vitro and In Vivo Activity against Candida auris

[4] E P Garvey, et al. J Antimicrob Chemother. The novel fungal CYP51 inhibitor VT-1598 is efficacious alone and in combination with liposomal amphotericin B in a murine model of cryptococcal meningitis

[5] Timothy J Break, et al. J Antimicrob Chemother. VT-1598 inhibits the in vitro growth of mucosal Candida strains and protects against fluconazole-susceptible and -resistant oral candidiasis in IL-17 signalling-deficient mice

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Catalog

Abmole Inhibitor Catalog

Keywords: VT-1598 supplier, Antifungal, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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