Antifungal Antifungal

Inhibitor

Cat.No.	Name	Information
M54743	4-Isopropylbenzoic acid	4-Isopropylbenzoic acid is an aromatic monoterpenoid isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid shows antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive mushroom tyrosinase inhibitor.
M53523	CRAMP (mouse)	CRAMP (mouse) is an antimicrobial peptide.
M45106	NP213 TFA	NP213 TFA is a rapid, novel, first-in-class synthetic antimicrobial peptide (AMP) with anti-fungal activity that targets fungal cytoplasmic membranes by perturbing and disrupting the membranes.NP213 is effective against nail fungal infections and is well tolerated.
M40510	Mutanocyclin	Mutanocyclin, a tetramic acids analog, is also a potent antifungal agent that inhibits mycelium formation in Candida albicans. In addition, Mutanocyclin also reduces the mRNA expression of HWP1, ECE1, FLO8, TEC1, and has inhibitory activity against immune cell infiltration.
M38728	(±)-Pinoresinol	(±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity.
M38723	Demethoxyencecalin	Demethoxyencecalin is a chromene isolated from Helianthus annuus, has antifungal activities.
M38717	Thiophanate-Methyl	Thiophanate-Methyl is a systematic fungicide.
M38715	Luteolin-7-rutinoside	Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
M31396	dl-Carvone	dl-Carvone is a monoterpene ketone found in the essential oils of medicinal plants, and is also a plant antifungal, as well as an insecticide with anti-inflammatory activity.
M30954	Isavuconazonium sulfate	Isavuconazonium sulfate (BAL8557-002), the proagent of the active triazole Isavuconazole, is an orally active antifungal agent. Isavuconazonium sulfate is used for invasive aspergillosis and mucormycosis.
M30416	Oxiconazole nitrate	Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.
M30368	Sulconazole	Sulconazole is a potent antifungal agent in the imidazole class. Sulconazole blocks the NF-κB/IL-8 signaling pathway and CSC (Cancer stem cells) formation. Sulconazole inhibits tumor growth, and can be used for breast cancer research.
M29191	VT-1598	VT-1598 is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris.
M28201	Quilseconazole	Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes.
M19383	Aegeline	Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity.
M19369	Geraniol	Geraniol, an olefinic terpene, was found to inhibit growth of Candida albicans and Saccharomyces cerevisiae strains.
M19308	Coniferin	Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization.
M18211	2-Hydroxy-1,4-naphoquinone	2-Hydroxy-1,4-naphoquinone
M17299	Xanthoxylin	Xanthoxylin has antifungal and antispasmodic activities. Xanthoxylin is isolated from Zanthoxylum simulans.
M17169	2-O-Methylanigorufone	2-O-Methylanigorufone (Methoxyanigorufone) is a natural product which can be from Monochoria vaginalis or Musa acuminata.

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